loader image
Disease and conditions A-Z

Obesity ups risk for intubation, death with COVID-19 in adults under 65

Obesity ups risk for intubation, death with COVID-19 in adults <65

(HealthDay)—Obesity is associated with an increased risk for intubation or death among hospitalized adults with COVID-19, with the association observed in adults younger than 65 years but not in older adults, according to a study published online July 29 in the Annals of Internal Medicine.

Michaela R. Anderson, M.D., from the Columbia University Irving Medical Center in New York City, and colleagues examined whether obesity is associated with intubation or death, inflammation, cardiac injury, or fibrinolysis in COVID-19 in a retrospective cohort study. Data were included from 2,466 adults hospitalized with severe acute respiratory syndrome coronavirus 2 infection during a 45-day period.

The researchers found that 22 percent of patients were intubated, 25 percent died, and 2 percent remained hospitalized during a median hospital length of stay of seven days. Patients with obesity had an increased risk for intubation or death compared with overweight patients, with the risk highest for class 3 obesity (hazard ratio, 1.6). The association was mainly seen for patients aged younger than 65 years and not in older patients. There was no association noted for body mass index with admission levels of biomarkers of inflammation, cardiac injury, or fibrinolysis.

“Additional investigations should evaluate potential mechanisms linking obesity and respiratory failure in COVID-19, including the role of specific inflammatory cytokines, complement-mediated endothelial cell dysfunction and thrombosis, and chest wall mechanics,” the authors write.

COVID-19 death rate high for patients with thoracic cancer

More information:
Abstract/Full Text

Copyright © 2020 HealthDay. All rights reserved.

Obesity ups risk for intubation, death with COVID-19 in adults under 65 (2020, August 3)
retrieved 3 August 2020
from https://medicalxpress.com/news/2020-08-obesity-ups-intubation-death-covid-.html

This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no
part may be reproduced without the written permission. The content is provided for information purposes only.

Source link

Show More

Related Articles

Leave a Reply

Your email address will not be published. Required fields are marked *

Back to top button